Common sequence variations in ABCG8 are related to plant sterol metabolism in healthy volunteers
نویسندگان
چکیده
منابع مشابه
Common sequence variations in ABCG8 are related to plant sterol metabolism in healthy volunteers.
Polymorphisms in the ATP binding cassette (ABC) transporters ABCG5 and ABCG8 are related to plasma plant sterol concentrations. It is not known whether these polymorphisms are also associated with variations in serum plant sterol concentrations during interventions affecting plant sterol metabolism. We therefore decided to study changes in serum plant sterol concentrations with ABCG5/G8 polymor...
متن کاملExecutive functions are related to serum testosterone and basal metabolism rate fluctuation but not lymphocyte dopamine receptor expression in the young healthy participants
Introduction: Herein, we evaluated linkages between EFs performances and dopamine receptor (DR) mRNA and testosterone level in the young Iranian male people. Methods: All 140 participants were normalized using depression, anxiety and stress scale questionnaire. Remained 108 volunteers were tested against drug abuse and then volunteers were distinguished by Wisconsin Card Sorting Test (WSC...
متن کاملSpinopelvic Parameters among Healthy Volunteers in Iran
Background: Recently, in approach to spinal pathologies, the whole spine should be considered as a biomechanicalunit. Studies have shown the great importance of sagittal and coronal balance and the relationship between the variousparts of spine together and pelvis. Former studies have shown a close relationship between spinopelvic parametersand sagittal balance. A complete und...
متن کاملPhenotypic differences in nebivolol metabolism and bioavailability in healthy volunteers
INTRODUCTION Nebivolol, a third-generation β-blocker, is subject to extensive first-pass metabolism and produces active β-blocking hydroxylated metabolites, like 4-OH-nebivolol. It is primarily a substrate of CYP2D6, a metabolic pathway that is under polymorphic genetic regulation. The objective of this study was to assess the metabolizer phenotype and to evaluate the interphenotype bioavailabi...
متن کاملSequence variations within protein families are linearly related to structural variations.
It is commonly believed that similarities between the sequences of two proteins infer similarities between their structures. Sequence alignments reliably recognize pairs of protein of similar structures provided that the percentage sequence identity between their two sequences is sufficiently high. This distinction, however, is statistically less reliable when the percentage sequence identity i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2005
ISSN: 0022-2275
DOI: 10.1194/jlr.m400210-jlr200